Drug discovery handbook /
The Drug Discovery Handbook gives professionals a tool to facilitate drug discovery by bringing together, for the first time in one resource, a compendium of methods and techniques that need to be considered when developing new drugs. This comprehensive, practical guide presents an explanation of th...
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| Online Access: |
Full text (MCPHS users only) |
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| Other Authors: | |
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Hoboken, N.J. :
Wiley-Interscience,
2005
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| Subjects: | |
| Local Note: | ProQuest Ebook Central |
Table of Contents:
- Drug discovery in the 21st century
- Natural products / Charles B. Spainhour
- Cancer cell proteomics using molecular aptamers / Weihong Tan [and others]
- Molecular similarity methods and QSAR models as tools for virtual screening / Jürgen Bajorath
- Systems biology : applications in drug discovery / Sean Ekins [and others]
- High throughput flow cytometry / Larry A. Sklar [and others]
- Combining NMR spectral information with associated structural features to form computationally nonintensive, rugged, and objective models of biological activity / Richard D. Beger, Dan A. Buzatu, and Jon G. Wilkes
- Using Microsoft Excel as a laboratory data management tool / A. Erik Rubin, Mark F. Russo, and William Neil.
- Age of regulation / Sandy Weinberg and Gerald J. Whartenby
- Simultaneous screening of multiple cell lines using the CellCard system / Oren E. Beske
- Protein X-ray crystallography in drug discovery / Peter Nollert [and others]
- Biological and chemistry assays available during drug discovery and developability assessment / Duane B. Lakings
- Strategies and methods in monitoring and targeting protein-protein interactions / Arianna Loregian and Giorgio Palù
- High-throughput screening : evolution of technology and methods
- Martyn N. Banks [and others]
- Metal-enhanced fluorescence : application to high-throughput screening and drug discovery / Kadir Aslan [and others].
- Methods for the design and analysis of replicate-experiment studies to establish assay reproducibility and the equivalence of two potency assays / Brian J. Eastwood [and others]
- Coupled luminescent methods in drug discovery : 3-minute assays for cytotoxicity and phosphatase activity / Michael J. Corey and Robert J. Kinders
- Design and pharmaceutical applications of prodrugs / Tomi Järvinen [and others]
- GABA and glutamate receptor ligands and their therapeutic potential in CNS disorders / Ulf Madsen [and others]
- Cardiac sarcolemmal ATP-sensitive potassium channel antagonists : novel ischemia-selective antiarrhythmic agents / George E. Billman.
- Factors influencing the efficacy of mediator-specific anti-inflammatory, glucocorticoid, and anticoagulant therapies for sepsis / Peter C. Minneci [and others]
- Combinatorial chemistry in the drug discovery process / Nathan T. Ross, Brian R. McNaughton, and Benjamin L. Miller
- Herbal medicines and animal models of gastrointestinal diseases / C.H. Cho and J.K.S. Ko
- Endocrine and metabolic agents / Brian L. Furman
- Respiratory viruses / Paul D. Olivo
- Strategies in the design of antiviral drugs / Erik De Clercq and Piet Herdewijn
- Protein kinase inhibitors in drug discovery / Keykavous Parang and Gongqin Sun
- RNA-based therapies / Steve Pascolo
- Novel imaging agents for molecular MR imaging of cancer / Dmitri Artemov and Zaver M. Bhujwalla
- Targets and approaches for cancer drug discovery / Susan L. Mooberry.
