From molecules to networks : an introduction to cellular and molecular /
An understanding of the nervous system at virtually any level of analysis requires an understanding of its basic building block, the neuron. The third edition of From Molecules to Networks provides the solid foundation of the morphological, biochemical, and biophysical properties of nerve cells. In...
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Full text (MCPHS users only) |
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| Other Authors: | , , |
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Amsterdam ; Boston :
Academic Press/Elsevier,
2014
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| Edition: | Third edition. |
| Subjects: | |
| Local Note: | ProQuest Ebook Central |
Table of Contents:
- Front Cover; From Molecules to Networks; Copyright Page; Contents; Preface to the Third Edition; Preface to the Second Edition; Preface to the First Edition; List of Contributors; I: CELLULAR AND MOLECULAR; 1 Cellular Components of Nervous Tissue; Neurons; General Features of Neuronal Morphology; Synapses and Spines; Synapses; Spines; Specific Examples of Different Neuronal Types; Inhibitory Local Circuit Neurons; Inhibitory Interneurons of the Cerebral Cortex; Inhibitory Projection Neurons; Medium-sized Spiny Cells; Purkinje Cells; Excitatory Local Circuit Neurons; Spiny Stellate Cells.
- Excitatory Projection NeuronsPyramidal Cells; Spinal Motor Neurons; Neuromodulatory Neurons; Dopaminergic Neurons of the Substantia Nigra; Neuroglia; Oligodendrocytes and Schwann Cells Synthesize Myelin; Astrocytes Play Important Roles in CNS Homeostasis; Astrocytes Have a Wide Range of Functions; Microglia are Mediators of Immune Responses in Nervous Tissue; Microglia Have Diverse Functions in Developing and Mature Nervous Tissue; Microglia Become Activated in Pathological States; Cerebral Vasculature; Transport of Molecules into the Brain; The Cerebral Vasculature in Disease States.
- The Lysosome is the Target Organelle in Several Inherited Diseases that Affect the Nervous SystemHow are Peripheral Membrane Proteins Targeted to their Appropriate Destinations?; Cytoplasmic Proteins are Also Compartmentalized; Summary; Cytoskeletons of Neurons and Glial Cells; Microtubules are an Important Determinant of Cell Architecture; Microfilaments and the Actin-Based Cytoskeleton are Involved in Intracellular Transport and Cell Movement; Intermediate Filaments are Prominent Constituents of Nervous Tissue; How Do the Various Cytoskeletal Systems Interact?; Summary.
- Molecular Motors in the Nervous SystemSummary; Building and Maintaining Nervous System Cells; Slow Axonal Transport Moves Soluble Proteins and Cytoskeletal Structures; Fast Axonal Transport is the Rapid Movement of Membrane Vesicles and Their Contents over Long Distances within a Neuron; How is Axonal Transport Regulated?; Summary; References; 3 Energy Metabolism in the Brain; Major Pathways of Brain Energy Metabolism; Fuel Delivery to Brain; Glycolytic Pathway: Generation of Pyruvate from Glucose; Redox Shuttling and Recycling Mechanisms: Oxidation of Pyruvate or Conversion to Lactate.
