Adverse Effects of Pertussis and Rubella Vaccines.
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| Other Authors: | , |
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Washington :
National Academies Press,
1990
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| Subjects: | |
| Local Note: | ProQuest Ebook Central |
Table of Contents:
- Adverse Effects of Pertussis and Rubella Vaccines; Copyright; Preface; Acknowledgments; Contents; Adverse Effects of PERTUSSIS and RUBELLA Vaccines; 1 Executive Summary ; METHODOLOGIC CONSIDERATIONS IN EVALUATING THE EVIDENCE; SUMMARY AND CONCLUSIONS; RESEARCH NEEDS; 2 Histories of Pertussis and Rubella Vaccines ; PERTUSSIS VACCINES; Epidemiology of Whooping Cough; Clinical Description; Diagnosis; Complications; Descriptive Epidemiology; Nature of the Causative Organism, B. pertussis; Major Milestones in the Development of Pertussis Vaccines; Whole-Cell Vaccines; Acellular Vaccines.
- Brief History of the Controversy Pertaining to Adverse Events Following Pertussis VaccinationRUBELLA VACCINES; Epidemiology of the Disease Rubella; Clinical Description; Diagnosis; Complications; Descriptive Epidemiology; Nature of the Rubella Virus; Major Milestones in the Development of Rubella Vaccines; Brief History of the Controversy Pertaining to Adverse Events Following Rubella Vaccination; REFERENCES; 3 Methodologic Considerations in Evaluating the Evidence ; THE NATURE OF THE EVIDENCE; QUESTIONS TO BE ADDRESSED; (1) Can vaccine cause the adverse event?
- (2) How frequently does vaccine cause the event?(3) Did vaccination cause a particular case of the adverse event?; THE BURDEN OF PROOF; CATEGORIES OF EVIDENCE; Experiments in Humans; Randomized Controlled Trials; Other Experimental Studies; Experiments in Animals: Animal Models; Controlled Epidemiologic Studies (Observational); Cohort Studies; Case-Comparison Studies; Other Controlled Studies; Case Reports and Case Series; Searching for Patterns; Historical Comparisons; Causation of the Individual Case; Monitoring System for Adverse Events Following Immunization; ASSESSMENT OF THE EVIDENCE.
- Evaluation of Single StudiesIntegration of the Collective Results; Meta-Analysis; Considerations in Inferring Causality; THE NATURE OF THE CONCLUSIONS; Quantitation; Resolution; Uncertainty and Confidence; Quality; Comprehensiveness; Neutrality; Judgment; SUMMARY OF THE EVIDENCE; REFERENCES; 4 Evidence Concerning Pertussis Vaccines and Central Nervous System Disorders, Including Infantile ... ; INFANTILE SPASMS; Clinical Description; Descriptive Epidemiology; History of Suspected Association with Pertussis Vaccines; Evidence from Studies in Humans; Case Reports and Case Series.
- Controlled Epidemiologic StudiesSummary; Conclusion; HYPSARRHYTHMIA; Clinical Description; Descriptive Epidemiology; History of Suspected Association with Pertussis Vaccines; Evidence from Studies in Humans; Case Reports and Case Series; Controlled Epidemiologic Studies; Summary; Conclusion; ASEPTIC MENINGITIS; Clinical Description; Descriptive Epidemiology; History of Suspected Association with Pertussis Vaccines; Evidence from Studies in Humans; Case Reports and Case Series; Controlled Epidemiologic Studies; Summary; Conclusion; ENCEPHALOPATHY; Clinical Description.
