Aspergillus and penicillium in the post-genomic era /

This book highlights some of the changes in the studies into these fungi, since the availability of genome sequences. The contributions vary from insights in the taxonomy of these genera, use of genomics for forward genetics and genomic adaptations, to specific stories addressing virulence, carbon s...

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Bibliographic Details
Online Access: Full text (MCPHS users only)
Other Authors: Vries, Ronald P. de (Editor), Gelber, Isabelle Benoit (Editor), Andersen, Mikael Rørdam (Editor)
Format: Electronic eBook
Language:English
Published: Norfolk, UK : Caister Academic Press, 2016
Subjects:
Local Note:ProQuest Ebook Central

MARC

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245 0 0 |a Aspergillus and penicillium in the post-genomic era /  |c edited by Ronald P. de Vries, Isabelole Benoit Gelber and Mikael Rørdam Andersen. 
264 1 |a Norfolk, UK :  |b Caister Academic Press,  |c [2016] 
264 4 |c ©2016 
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504 |a Includes bibliographical references and index. 
505 0 |a Intro -- Contents -- Contributors -- Current Books of Interest -- Preface -- 1. Taxonomy of Aspergillus, Penicillium and Talaromyces and its Significance for Biotechnology -- Introduction -- Phylogeny of Eurotiales -- Species and species concepts -- Single name nomenclature and its impact on applied mycology -- New species, new names -- Aspergillus, Penicillium and Talaromyces and related genera -- Conclusion -- 2. Comparative Genomics, Resequencing and Fast Forward Genetics in Aspergillus and Penicillium -- Introduction -- Resequencing and fast forward genetics -- The aspergilli -- Penicillium -- Conclusions -- Future trends -- 3. Diversity and Mechanisms of Genomic Adaptation in Penicillium -- Introduction -- Ecological niches and life history traits -- Phylogenetic relationships, genome size and content, and changes in gene content -- Horizontal gene transfers -- Transcriptomics -- Population genetic diversity within Penicillium species and mode of reproduction -- Conclusions and future prospects -- 4. Approaches for Comparative Genomics in Aspergillus and Penicillium -- Introduction -- Current status of genomics -- Available genome databases with comparative genomics capabilities -- General methods for comparative genomics -- Primary metabolism -- Secondary metabolism -- Secretome analysis and plant polysaccharide degradation -- Other comparative 'omics' -- Future perspectives -- what can we learn from bacteria? -- 5. Blue Mould to Genomics and Beyond: Insights into the Biology and Virulence of Phytopathogenic Penicillium Species -- Introduction -- Current status of blue mould research -- Current status of Penicillium genomics -- Future trends -- 6. Post-genomic Approaches to Dissect Carbon Starvation Responses in Aspergilli -- Introduction -- Controlled cultivation of filamentous fungi to study starvation responses. 
505 8 |a Carbon starvation responses -- Morphological responses during C-limitation -- Recycling responses to deal with carbon starvation -- Co-regulation of conidiogenesis and cell wall hydrolase production -- Regulation of extracellular protease formation during carbon starvation -- Conclusions and future trends -- 7. Genetics and Physiology of Sulfur Metabolism in Aspergillus -- Introduction -- Synthesis of cysteine and methionine -- Sulfur metabolite repression -- Dysregulation of sulfur metabolism in cys and scon mutants induces stress responses -- Transcription factors controlling sulfur metabolism -- Other regulatory systems in sulfur metabolism -- Future trends -- 8. Production of Feruloyl Esterases by Aspergillus Species -- Introduction -- Materials and methods -- Results -- Discussion -- Conclusion -- 9. Secondary Metabolite Formation by the Filamentous Fungus Penicillium chrysogenum in the Post-genomic Era -- Introduction -- Fungal secondary metabolite enzymes -- Secondary metabolite gene clusters and their products in P. chrysogenum -- Approaches for the activation of 'silent' secondary metabolite gene clusters -- Conclusions and future trends -- 10. pH Modulation by Fungal Secreted Effecting Molecules: A Mechanism Affecting Pathogenicity and Mycotoxin Accumulation During Colonization by Penicillium expansum -- Introduction -- Small secreted molecules affect fungal biology -- Fungal small secreted molecules modulate environmental pH and pathogenicity -- GLA requirement for colonization and conidiation by P. expansum -- pH and gene activation -- pH and secondary metabolism of patulin production -- The effect of acidification by GLA accumulation on patulin and pathogenicity of P. expansum -- Modulating the activation of small secreted molecules. 
505 8 |a 11. Evolutionary Adaptation as a Tool to Generate Targeted Mutant Strains as Evidenced by Increased Inulinase Production in Aspergillus oryzae -- Introduction -- Materials and methods -- Results and discussion -- Index. 
520 |a This book highlights some of the changes in the studies into these fungi, since the availability of genome sequences. The contributions vary from insights in the taxonomy of these genera, use of genomics for forward genetics and genomic adaptations, to specific stories addressing virulence, carbon starvation, sulphur metabolism, feruloyl esterases, secondary metabolism and pH modulation, to the development of novel methodology for use in parallel to genome sequencing. It therefore provides a taste of the current status of research in Penicillium and Aspergillus and a promise of many more thing. 
588 0 |a Online resource; title from PDF title page (EBSCO, viewed August 8, 2016). 
590 |a ProQuest Ebook Central  |b Ebook Central Academic Complete 
650 0 |a Aspergillus. 
650 0 |a Aspergillus  |x Genetics. 
650 0 |a Penicillium. 
650 0 |a Penicillium  |x Genetics. 
700 1 |a Vries, Ronald P. de,  |e editor. 
700 1 |a Gelber, Isabelle Benoit,  |e editor. 
700 1 |a Andersen, Mikael Rørdam,  |e editor. 
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