Essential Guide to Blood Groups.
A short, up-to-date text on blood groups, for people working or training in the field of blood transfusion, transplantation, or human genetics, but who are not specialising in the field of blood groups, the third edition of Essential Guide to Blood Groups is a pocket-sized book, containing full colo...
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Full text (MCPHS users only) |
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| Main Author: | |
| Other Authors: | |
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Hoboken :
Wiley,
2013
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| Edition: | 3rd ed. |
| Subjects: | |
| Local Note: | ProQuest Ebook Central |
Table of Contents:
- Essential Guide to Blood Groups; Copyright; Contents; Abbreviations; 1 An introduction to blood groups; What is a blood group?; Blood group antibodies; Clinical importance of blood groups; Biological importance of blood groups; Blood group systems; Blood group terminology and classification; 2 Techniques used in blood grouping; Factors affecting antigen-antibody reactions; Temperature; Time and ionic strength; pH; Antigen density; Stages of haemagglutination reactions; Direct agglutination; Indirect agglutination; Enzyme techniques; Antiglobulin tests; Elution techniques.
- Automation of test proceduresFlow cytometry; Molecular blood group genotyping; 3 The ABO blood groups; Introduction; ABO antigens, antibodies, and inheritance; A1 and A2; Antigen, phenotype, and gene frequencies; ABO antibodies; Importance of the ABO system to transfusion and transplantation medicine; Biochemical nature of the ABO antigens; Biosynthesis of the ABO antigens and ABO molecular genetics; H, the precursor of A and B; ABH secretion; H-deficient red cells; Further complexities; Acquired changes; Associations with disease and functional aspects; 4 The Rh blood group system.
- Introduction
- Rh, not rhesusHaplotypes, genotypes, and phenotypes; Biochemistry and molecular genetics; D antigen (RH1); Molecular basis of the D polymorphism; D variants; Clinical significance of anti-D; D testing; C, c, E, and e antigens (RH2, RH4, RH3, RH5); Clinical significance of CcEe antibodies; Molecular basis of the C/c and E/e polymorphisms; Other Rh antigens; Compound antigens: ce, Ce, CE, cE (RH6, RH7, RH22, RH27), and G (RH12); Cw, Cx, and MAR (RH8, RH9, RH51); VS and V (RH20, RH10); Rh-deficient phenotypes
- Rh null and Rh mod; Putative function of the Rh proteins and RhAG.
- 5 Other blood groupsThe Kell system; The Kell glycoprotein and the KEL gene; Kell system antigens; Kell system antibodies; Ko phenotype; McLeod syndrome, McLeod phenotype, and Kx (XK1) antigen; The Duffy system; Fya (FY1) and Fyb (FY2); Anti-Fya and -Fyb; Fy3 and Fy5; The Duffy-glycoprotein, a receptor for chemokines; Duffy and malaria; The Kidd system; Jka (JK1) and Jkb (JK2); anti-Jka and -Jkb; Jk(a-b- ) and Jk3; The Kidd-glycoprotein is a urea transporter; The MNS system; M (MNS1) and N (MNS2); anti-M and -N; S (MNS3) and s (MNS4); anti-S and -s; S- s- U- phenotype and anti-U.
- Other MNS antigens and antibodiesThe Diego system; Band 3, the red cell anion exchanger; Dia (DI1) and Dib (DI2); anti-Dia and -Dib; Wra (DI3) and Wrb (DI4); anti-Wra and -Wrb; Other Diego-system antigens; The Lewis System; Some other blood group systems; P1PK; Lutheran; Yt; Xg; Scianna; Dombrock; Colton; Landsteiner-Wiener (LW); Chido/Rodgers; Gerbich; Cromer; Knops; Indian; I; JR and Lan; Vel; Antigens that do not belong to a blood group system; 6 Clinical significance of blood group antibodies; Antibody production and structure; Factors affecting the clinical significance of antibodies.
