MicroRNAs in medicine /
"MicroRNAs in Medicine provides an access point into the current literature on microRNA for both scientists and clinicians, with an up-to-date look at what is happening in the emerging field of microRNAs and their relevance to medicine. Each chapter is a comprehensive review, with descriptions...
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Full text (MCPHS users only) |
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| Format: | Electronic eBook |
| Language: | English |
| Published: |
Hoboken, New Jersey :
Wiley-Blackwell,
2013
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| Subjects: | |
| Local Note: | ProQuest Ebook Central |
Table of Contents:
- ""Title page""; ""Copyright page""; ""Foreword""; ""Preface""; ""Contributors""; ""1: MicroRNAs: A Brief Introduction""; ""I. A Short History of Small RNAs""; ""II. Biogenesis of miRNAs""; ""III. miRNA Function: Controlling mRNA Stability, Degradation, and/or Translation""; ""IV. Regulating the Regulators: miRNA Control and Dysfunction in Disease""; ""V. Present and Future Perspectives for miRNAs in Medicine""; ""PART I: MicroRNAs as Physiological Regulators""; ""2: MicroRNA Regulation of Stem Cell Fate and Reprogramming""; ""I. Introduction""
- ""II. MicroRNAs in Pluripotency and Establishment of Different Lineages""""III. MicroRNAs, Induced Pluripotency, and Transdifferentiation""; ""IV. Conclusion""; ""Acknowledgments""; ""3: MicroRNAs as Regulators of Immunity""; ""I. Introduction""; ""II. Innate Immunity and miRNAs""; ""III. Adaptive Immunity and miRNAs""; ""IV. Conclusions and Future Directions""; ""4: Regulation of Senescence by MicroRNAs""; ""I. Introduction: Senescence""; ""II. Posttranscriptional Regulation of Senescence by miRNAs""; ""III. Impact of SA-miRNAs on In Vivo Senescence""
- ""IV. Concluding Remarks and Future Perspectives""""Acknowledgments""; ""5: The Emergence of GeroMIRs: A Group of MicroRNAs Implicated in Aging""; ""I. Introduction""; ""II. MiRNAs and Aging: Lessons from Invertebrates""; ""III. Changes in miRNA Expression during Mammalian Aging""; ""IV. MiRNA Modulation of Mammalian DNA Damage""; ""V. Micromanaging of Other Aging-Associated Pathways in Mammals""; ""VI. Conclusions and Future Perspectives""; ""6: MicroRNAs and Hematopoiesis""; ""I. Introduction""; ""II. Lymphocyte Development""; ""III. Monocyte and Granulocyte Development""
- ""IV. Erythrocyte and Megakaryocyte Development""""V. Conclusions""; ""7: MicroRNAs in Platelet Production and Activation""; ""I. Introduction""; ""II. miRNA Biogenesis and Function""; ""III. miRNAs and Megakaryocytopoiesis""; ""IV. Platelet miRNAs""; ""V. Platelet miRNAs as Biomarkers""; ""VI. Platelet Microparticles and miRNAs""; ""VII. Summary and Future Directions""; ""PART II: MicroRNAs in Infectious Disease: Hostâ€"Pathogen Interactions""; ""8: MicroRNAs as Key Players in Host-Virus Interactions""; ""I. Introduction""; ""II. Host miRNAs and Virus Infection""; ""III. Viral miRNAs""
- ""IV. Biological Roles of Viral miRNAs""""V. Conclusions and Future Prospects""; ""Acknowledgments""; ""9: MicroRNA Expression in Avian Herpesviruses""; ""I. Introduction""; ""II. Avian Herpesviruses and Associated Diseases""; ""III. Identification of miRNAs Encoded by Avian HerpesvirusES""; ""IV. Viral Orthologues of Host miRNAs""; ""V. Target Identification of Avian Herpesvirus miRNAs""; ""VI. Conclusions""; ""Acknowledgment""; ""10: Function of Human Cytomegalovirus MicroRNAs and Potential Roles in Latency""; ""I. Introduction to Human Cytomegalovirus""
