Principles of downstream techniques in biological and chemical processes /

"Downstream processing is an essential practice in the production and purification of biosynthethic materials, which is especially important in the production of pharmaceutical products. This book covers the fundamentals and the design concepts of various downstream recovery and purification st...

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Bibliographic Details
Online Access: Full text (MCPHS users only)
Main Author: Doble, Mukesh (Author)
Format: Electronic eBook
Language:English
Published: Oakville, ON, Canada : Apple Academic Press, 2015
Subjects:
Local Note:ProQuest Ebook Central

MARC

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100 1 |a Doble, Mukesh,  |e author. 
245 1 0 |a Principles of downstream techniques in biological and chemical processes /  |c Mukesh Doble, PhD, FRSC. 
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264 1 |a Oakville, ON, Canada :  |b Apple Academic Press,  |c 2015. 
300 |a 1 online resource 
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504 |a Includes bibliographical references and index. 
505 0 |a 1. Downstream processing principles, economics and issues -- 2. Importance of downstream in industrial processes : examples -- 3. Size reduction cell breakage and recovery of intracellular material -- 4. Isolation of insolubles -- 5. Product recovery -- 6. Product enrichment -- 7. Product polishing and finishing -- 8. Utilities and auxiliary processes -- 9. Future trends -- 10. Fundamental concepts. 
520 |a "Downstream processing is an essential practice in the production and purification of biosynthethic materials, which is especially important in the production of pharmaceutical products. This book covers the fundamentals and the design concepts of various downstream recovery and purification steps (unit operations) involved in biochemical and chemical processes. The book covers cell breakage and recovery of intracellular material, isolation of solids, product recovery, product enrichment, and product polishing and finishing. It also covers basic chemical engineering purification techniques such as distillation, absorption, adsorption, etc. Described in the book are several case studies that discuss the various unit operation in each of the processes. An important point to consider is the economics of the downstream operation, and this book provides practical information on capital costs and operating expenses in addition to other operating cost factors with respect to downstream processing. Green chemistry and safety issues are also addressed. Practicing chemical engineers in biotechnology, pharmaceutical chemistry, and other areas will find this book valuable as a reference on downstream techniques used in biological processes. Students in chemical engineering would benefit from this book as well."--  |c Provided by publisher 
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