New Aspects of the Renin Angiotensin System in Cardiovascular and Renal Diseases.

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Bibliographic Details
Online Access: Full text (MCPHS users only)
Main Author: Casarini, Dulce Elena
Other Authors: Arita, Danielle Yuri, Cunha, Tatiana Sousa
Format: Electronic eBook
Language:English
Published: Sharjah : Bentham Science Publishers, 2016
Subjects:
Local Note:ProQuest Ebook Central
Table of Contents:
  • FOREWORD ; PREFACE ; List of Contributors ; Renin Angiotensin System: Old System with New Different Components ; INTRODUCTION; RAAS at Present; ACE2; Chymase ; Angiotensin III and IV ; Angiotensin (1-7); Angiotensin (1-12); Angiotensin A ; Alamandine ; PERSPECTIVES ; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES; The Important Role of Systemic and Local Renin-Angiotensin System ; CLASSICAL AND NEW VISION OF THE RAS; Tissue Sites of Local RAS; The Intracellular RAS; The Circulating and Local RAS in Cardiovascular and Renal Homeostasis; In the Heart; In the Kidney.
  • Role of the RAS in Cardiac and Chronic Kidney DiseasesBlocking the Systemic and Local RAS; Optimizing RAS Blockade; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES; Renin-Angiotensin System and Cardiovascular Physiology ; RAS & CARDIOVASCULAR SYSTEM: AN OVERVIEW ; RAS & ELEVATED BLOOD PRESSURE ; RAS & SYMPATHETIC OVERACTIVITY; RAS & ENDOTHELIAL AND VASCULAR DYSFUNCTIONS; RAS & CARDIAC HYPERTROPHY ; RAS & IMMUNE RESPONSE ACTIVATION; RAS INHIBITORS & CARDIOVASCULAR DISEASE TREATMENT: PHYSIOLOGICAL BASIS ; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES.
  • Cardiac Intracellular Renin-Angiotensin System INTRODUCTION ; Hormones; The Renin-Angiotensin System; THE INTRACRINE RAS; Early Studies with Isolated Nuclei; Studies with Intact Isolated Cells; Studies with Animals; THE INTRACELLULAR RAS IN THE HEART; Intracellular RAS; Intracellular Synthesis of Ang II in the Heart; Role of the Endogenous Intracellular RAS In Cardiac Function; SIGNIFICANCE OF THE INTRACELLULAR RAS IN THE HEART; CONFLICT OF INTEREST; ACKNOWLEDGMENTS; REFERENCES; Angiotensin-(1-7) in the Heart ; INTRODUCTION; Renin Angiotensin-System Cascade.
  • Angiotensin-(1-7) Formation in the HeartCardiac Rhythma; Coronary Flow; Anti-Hypertrophic and Anti-Fibrotic Actions; CONCLUSION; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES; Essential Roles of Renin-Angiotensin System in the Kidney ; INTRODUCTION; RAS
  • Bioactive Angiotensins and Receptors; RAS Production in the Kidney; Ang II; Ang II Actions in the Glomerulus; Ang II Actions in the Proximal Tubules; Ang II Actions in the Thick Ascending Limbs; Ang II in the Distal Tubules; Ang II Actions in the Collecting Ducts; Ang II and Water Balance; Ang-(1-7).
  • Ang-(1-7) Actions in Proximal TubuleAng-(1-7) Actions in the Distal Tubule; Ang-(1-7) and Water Balance; Ang III Actions in the Kidney; Ang IV Actions in the Kidney; CONCLUSION; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES; Renin-Angiotensin System Along the Nephron and its Role in Hypertension ; INTRODUCTION; Intratubular Ang II and AT1R Along the Nephron; Increased Expression of AGT in Proximal Tubules in Hypertension; Renin in the Collecting Duct ; The (Pro) Renin Receptor; Renin and PRR Upregulation During Angiotensin II-Dependent Hypertension.; CONCLUSION; CONFLICT OF INTEREST.