Opportunities for organ donor intervention research : saving lives by improving the quality and quantity of organs for transplantation /
The organ donation and transplantation system strives to honor the gift of donated organs by fully using those organs to save and improve the quality of the lives of their recipients. However, there are not enough donated organs to meet the demand and some donated organs may not be recovered, some r...
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| Format: | Electronic eBook |
| Language: | English |
| Published: |
Washington, DC :
National Academies Press,
2017
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| Series: | Consensus study report.
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| Subjects: | |
| Local Note: | ProQuest Ebook Central |
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| 245 | 0 | 0 | |a Opportunities for organ donor intervention research : |b saving lives by improving the quality and quantity of organs for transplantation / |c Catharyn T. Liverman, Sarah Domnitz, James F. Childress, editors ; Committee on Issues in Organ Donor Intervention Research, Board on Health Sciences Policy, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine. |
| 264 | 1 | |a Washington, DC : |b National Academies Press, |c [2017] | |
| 300 | |a 1 online resource (1 PDF file (xii, 158 pages)) : |b illustrations | ||
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| 490 | 1 | |a A consensus study report of the National Academies of Sciences, Engineering, Medicine | |
| 504 | |a Includes bibliographical references. | ||
| 505 | 0 | |a Introduction -- Ethical framework -- Legal, regulatory, and policy frameworks for organ donation and research participation -- Research approval, implementation, and oversight: ensuring quality and trust -- Appendixes. | |
| 505 | 0 | |a Introduction -- Ethical framework -- Legal, regulatory, and policy frameworks for organ donation and research participation -- Research approval, implementation, and oversight: ensuring quality and trust. | |
| 520 | 3 | |a The organ donation and transplantation system strives to honor the gift of donated organs by fully using those organs to save and improve the quality of the lives of their recipients. However, there are not enough donated organs to meet the demand and some donated organs may not be recovered, some recovered organs may not be transplanted, and some transplanted organs may not function adequately. Organ donor intervention research can test and assess interventions (e.g., medications, devices, and donor management protocols) to maintain or improve organ quality prior to, during, and following transplantation. The intervention is administered either while the organ is still in the deceased donor or after it is recovered from the donor but before it is transplanted into a recipient. Organ donor intervention research presents new challenges to the organ donation and transplantation community because of ethical questions about who should be considered a human subject in a research study, whose permission and oversight are needed, and how to ensure that such research does not threaten the equitable distribution of a scarce and valuable resource. Opportunities for Organ Donor Intervention Research focuses on the ethical, legal, regulatory, policy, and organizational issues relevant to the conduct of research in the United States involving deceased organ donors. This report provides recommendations for how to conduct organ donor intervention research in a manner that maintains high ethical standards, that ensures dignity and respect for deceased organ donors and their families, that provides transparency and information for transplant candidates who might receive a research organ, and that supports and sustains the public's trust in the process of organ donation and transplantation. | |
| 536 | |a This activity was supported by contracts between the National Academy of Sciences and the American Association for the Study of Liver Diseases, American Society of Transplant Surgeons, American Society of Transplantation, Association of Organ Procurement Organizations, Gift of Life Donor Program, Health Resources & Services Administration (Contract No. HHSH250201500001I), Laura and John Arnold Foundation, National Institutes of Health (National Heart, Lung, and Blood Institute; National Institute of Allergy and Infectious Diseases; National Institute of Diabetes and Digestive and Kidney Diseases) (Contract No. HHSN26300092), National Kidney Foundation, OneLegacy Foundation, and The Transplantation Society. Any opinions, findings, conclusions, or recommendations expressed in this publication do not necessarily reflect the views of any organization or agency that provided support for the project. | ||
| 588 | 0 | |a Online resource; title from PDF title page (viewed February 26, 2018). | |
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| 650 | 0 | |a Organ donors |x Research |z United States. | |
| 650 | 0 | |a Organ donors |x Research |x Moral and ethical aspects |z United States. | |
| 650 | 0 | |a Donation of organs, tissues, etc. |z United States. | |
| 650 | 0 | |a Donation of organs, tissues, etc. |x Law and legislation |z United States. | |
| 650 | 0 | |a Donation of organs, tissues, etc. |x Government policy |z United States. | |
| 650 | 0 | |a Preservation of organs, tissues, etc. | |
| 650 | 0 | |a Transplantation of organs, tissues, etc. | |
| 650 | 0 | |a Organ donors. | |
| 650 | 1 | 2 | |a Organ Preservation |
| 650 | 2 | 2 | |a Tissue and Organ Procurement |
| 650 | 2 | 2 | |a Biomedical Research |x organization & administration |
| 650 | 2 | 2 | |a Organ Transplantation |
| 650 | 2 | 2 | |a Tissue Donors |
| 650 | 2 | 2 | |a Consensus |
| 700 | 1 | |a Liverman, Catharyn T., |e editor. | |
| 700 | 1 | |a Domnitz, Sarah Brooke, |e editor. | |
| 700 | 1 | |a Childress, James F., |e editor. | |
| 710 | 2 | |a National Academies of Sciences, Engineering, and Medicine (U.S.). |b Committee on Issues in Organ Donor Intervention Research, |e issuing body. | |
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