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|a 636.0896992
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|a Meuten, Donald J.
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| 245 |
1 |
0 |
|a Tumors in Domestic Animals.
|
| 250 |
|
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|a 5th ed.
|
| 260 |
|
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|a Somerset :
|b Wiley,
|c 2016.
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| 300 |
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|a 1 online resource (1000 pages)
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| 336 |
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|b txt
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| 500 |
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|a Cancer of€unknown primary site.
|
| 504 |
|
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|a Includes bibliographical references and index.
|
| 505 |
0 |
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|a Title Page ; Copyright Page; Contents; List of€Contributors; Preface; Chapter 1 An Overview of€Molecular Cancer Pathogenesis, Prognosis, and Diagnosis; Fundamentals of€cancer biology; Genetic injury; Epigenetics; Tumor heterogeneity, tumor progression, and€clonal evolution; The hallmarks of€malignancy; Sustaining proliferative signaling: proto-oncogenes and oncogenes ; Evading growth suppressors; Resisting cell death; Enabling reproductive immortality; Inducing angiogenesis; Activating invasion and€metastasis; References.
|
| 505 |
8 |
|
|a Veterinary cancer incidence and€molecular approaches to€diagnosis and€prognosisGenetics and€cancer; From concepts to€clinics: molecular genetics usher in€an€era of€opportunity; Cytogenetics in€cancer; Molecular diagnostics and€prognostics; Evolutionarily conserved genomic changes in€cancers; Molecular assays in€veterinary oncology; Conclusions; References; Chapter 2 Trimming Tumors for€Diagnosis and€Prognosis; Specimen sizing; Orientation of€trimmed specimens; Perpendicular margins; Parallel margins (en face); Margin evaluation; Skin tumors; Canine soft tissue sarcomas and€mast cell€tumors.
|
| 505 |
8 |
|
|a Digital amputationsLimb amputations; Ears; Eyelids; Intraocular tumors; Hemimandibulectomies/maxillectomies; Gastrointestinal tumors; Tumors of€parenchymal organs; Tumors of€lobar parenchymal organs; Lymph nodes; References; Chapter 3 Immunohistochemistry: Fundamentals and€Applications in€Oncology; Introduction; References; The immunohistochemical test; Fixation and€processing; References; Antigen retrieval; Enzymatic retrieval; Heat-induced epitope retrieval (HIER) ; References; Antigens and€antibodies; Antigens; Antibodies; Affinity; Avidity; Polyclonal antibodies; Monoclonal antibodies.
|
| 505 |
8 |
|
|a What makes an€antibody good for€immunohistochemistry?References; Detection methods; Avidin-biotin methods; Polymeric labeling two-step method ; Catalyzed signal amplification; Immunohistochemistry on€mouse tissues; References; Storage and€handling of€reagents; References; Controls in€immunohistochemistry; Positive tissue control; Negative tissue control; Reagent (antibody) controls; Methods for high-throughput evaluation of control tissues ; References; Standardization (optimization) and€validation€of€a€new IHC test; Primary antibody standardization and€validation.
|
| 505 |
8 |
|
|a Laboratory validation of€the€IHC testClinical validation of€the€IHC test; References; Immunohistochemical report and€interpretation; Patterns of€specific labeling; Patterns of€nonspecific labeling; What constitutes a€positive/significant result?; Distinguishing true-positive from false-positive immunoreactivity ; References; Troubleshooting the€IHC test; Background staining; References; Approach to€the€immunohistochemical characterization of€tumors; Biomarkers in€diagnostic immunohistochemistry of€neoplasms; Prognostic markers and€immunohistochemistry; References.
|
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|a Print version record.
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|a ProQuest Ebook Central
|b Ebook Central College Complete
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|a Tumors in animals.
|
| 650 |
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|a Veterinary oncology.
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| 650 |
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|a Domestic animals.
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|a Neoplasms
|x veterinary
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2 |
|a Animals, Domestic
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|a Meuten, Donald J.
|t Tumors in Domestic Animals.
|d Somerset : Wiley, ©2016
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