Vanilloid Receptor TRPV1 in Drug Discovery : Targeting Pain and Other Pathological Disorders /

This book discusses recent advances in biology, chemistry, and pharmacology at both the preclinical and clinical stage of transient receptor potential vanilloid subtype 1 (TRPV1) drug discovery research. Chapters explore the impact and drug targeting of TRPV1 in inflammation, migraine, arthritis, an...

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Bibliographic Details
Online Access: Full text (MCPHS users only)
Other Authors: Gomtsyan, Arthur, Faltynek, Connie R.
Format: Electronic eBook
Language:English
Published: Hoboken, N.J. : Wiley, 2010
Subjects:
Local Note:ProQuest Ebook Central
Table of Contents:
  • TRP channels and human diseases / Bernd Nilius and Rudi Vennekens
  • Role of TRP channels in pain : an overview / Arpad Szallasi
  • Biochemical pharmacology of TRPV1 : molecular integrator of pain signals / Carol S. Surowy, Philip R. Kym, Regina M. Reilly
  • TRPV1 genetics / Ruslan Dorfman [and others]
  • TRPV1 and inflammatory pain / Anindya Bhattacharya, Sonya G. Lehto, and Narender R. Gavva
  • Role of TRPV1 receptors in osteoarthritis pain / Shailen K. Joshi and Prisca Honore
  • TRPV1 and bone cancer pain / Juan Miguel Jimenez-Andrade and Patrick Mantyh
  • TRPV1 in visceral pain and other visceral disorders / Antonio Avelino and Francisco Cruz
  • TRPV1 receptors and migraine / Philip R. Holland and Peter J. Goadsby
  • TRPV1 in neuropathic pain, and neurological and neuropsychiatric disorders / Enza Palazzo [and others]
  • Aryl-urea class and related TRPV1 antagonists / Arthur Gomtsyan
  • 2-pyridinylpiperazine carboxamide class and related TRPV1 antagonists / Natalie A. Hawryluk and Nicholas I. Carruthers
  • TRPV1 agonist approaches for pain management / Keith R. Bley
  • The TRPV1 channel in normal thermoregulation : what have we learned from experiments using different tools? / Andras Garami [and others]
  • Role of TRPV1 in respiratory diseases / Serena Materazzi [and others]
  • Role of TRPV1 in diabetes / Hubert Tsui [and others].