Function of microRNAs in skeletal muscle cell differentiation.
Skeletal muscle cell differentiation is exogenously regulated by cytokines and growth factors and it is post-transcriptionally regulated by microRNAs (miRNAs). This study presents miRNA and gene expression data of differentiating skeletal muscles with or without concomitant TNF-alpha or IGF1 exposur...
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| Online Access: |
Full text (MCPHS users only) |
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| Main Author: | |
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Göttingen :
Cuvillier Verlag,
2016
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| Subjects: | |
| Local Note: | ProQuest Ebook Central |
| Summary: | Skeletal muscle cell differentiation is exogenously regulated by cytokines and growth factors and it is post-transcriptionally regulated by microRNAs (miRNAs). This study presents miRNA and gene expression data of differentiating skeletal muscles with or without concomitant TNF-alpha or IGF1 exposure to elucidate the function of miRNAs. Results indicate specific miRNA-target relations during skeletal muscle differentiation and show that miRNAs mediate the effect of TNF-alpha. |
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| Physical Description: | 1 online resource (93 pages) |
| ISBN: | 3736983069 9783736983069 |
| Source of Description, Etc. Note: | Print version record. |
