Humanized mice /

Annotation In a humanized mouse transplanted human tissues and cells show the same biological function as they do in the human body. It has become possible to study the pathophysiology and treatment of human diseases in mice with excellent reproducibility, a remarkable breakthrough. Unsurprisingly,...

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Bibliographic Details
Online Access: Full text (MCPHS users only)
Other Authors: Nomura, Tatsuji, 1922-2013 (Editor), Watanabe, Takeshi, 1940- (Editor), Habu, Sonoko (Editor)
Format: Electronic eBook
Language:English
Published: Berlin ; [London?] : Springer, 2008
Series:Current topics in microbiology and immunology ; 324.
Subjects:
Local Note:ProQuest Ebook Central
Table of Contents:
  • Basic Concept of Development and Practical Application of Animal Models for Human Diseases
  • Humanized SCID Mouse Models for Biomedical Research
  • NOD/Shi-scid IL2r?null (NOG) Mice More Appropriate for Humanized Mouse Models
  • Humanizing Bone Marrow in Immune-Deficient Mice
  • The Differentiative and Regenerative Properties of Human Hematopoietic Stem/Progenitor cells in NOD-SCID/IL2r?null Mice
  • Antigen-Specific Antibody Production of Human B Cells in NOG Mice Reconstituted with the Human Immune System
  • Humanized Immune System (HIS) Mice as a Tool to Study Human NK Cell Development
  • Human T Cell Development and HIV Infection in Human Hemato-Lymphoid System Mice
  • Humanized Mice for Human Retrovirus Infection
  • Functional and Phenotypic Characterization of the Humanized BLT Mouse Model
  • Novel Metastasis Models of Human Cancer in NOG Mice
  • In Vivo Imaging in Humanized Mice.