How Fat Works.

Annotation An experimental pathologist and molecular geneticist, Philip Wood uses gene-knockout technology to study the way mouse genes regulate the metabolism of fat - research that provides insights into the workings of fatty-acid metabolism in humans and what can happen when that metabolic balanc...

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Bibliographic Details
Online Access: Full text (MCPHS users only)
Main Author: Wood, Philip A.
Format: Electronic eBook
Language:English
Published: Cambridge : Harvard University Press, 2009
Subjects:
Local Note:ProQuest Ebook Central

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505 0 |a Acknowledgments; Abbreviations; Introduction: Lessons from a Mouse; I. Problems of Excess Fat and Cholesterol; 1. The Burden of Obesity ; 2. Testing for Silent Diseases ; 3. An Introduction to the Terminology; 4. Disorders of Excess Cholesterol and Triglycerides; 5. Insulin Resistance and Metabolic Syndrome; 6. Type 1 and Type 2 Diabetes; II. Dynamics of Fat Metabolism; 7. The Energy Equation; 8. Making and Storing Fat; 9. Burning Fat in the Cell; 10. Single-Gene Disorders of Lipid Metabolism; 11. Multifactorial Genetic Diseases of Lipid Metabolism; III. Knowledge into Practice. 
505 8 |a 12. Overcoming Genetics and Aging13. Breaking the Insulin Cycle; 14. Exercise to Burn Fat; 15. Lipid-Lowering Drugs; 16. Practical Lessons for Making Good Decisions; IV. The Environment; 17. Nutrient Labeling; 18. Alternative Medicine and Fad Diets; 19. Media Coverage of Health Research; Glossary; References; Index. 
520 8 |a Annotation An experimental pathologist and molecular geneticist, Philip Wood uses gene-knockout technology to study the way mouse genes regulate the metabolism of fat - research that provides insights into the workings of fatty-acid metabolism in humans and what can happen when that metabolic balance goes awry. Based on the classes he regularly teaches to first- and second-year medical students, Wood's book reviews the individual and public health burden of obesity and clarifies often-used, but often inadequately explained, terms employed in the continuing cultural and scientific debate about excess fat. He explains the role of fat in the healthy body, how fat is made, stored, and burned, and demonstrates how excess fat can lead to an array of metabolic disorders and diseases, from hypercholesterolemia and insulin resistance to diabetes. He reviews what recent research can tell us about specific genes or groups of genes that can lead to specific metabolic disorders. He explains the science behind common weight-loss regimens and why those regimens might succeed or fail, and reviews the complex interplay of hormones, genes, and stress in the way our bodies deal with fat through the life cycle. How Fat Worksis a concise, clear, and up-to-date primer on the workings of fat, and essential reading for professionals entering careers in medicine and public health administration or anyone wanting a better understanding of one of our most urgent health crises. 
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