Analyzing biomolecular interactions by mass spectrometry /
This monograph reviews all relevant technologies based on mass spectrometry that are used to study or screen biological interactions in general. Arranged in three parts, the text begins by reviewing techniques nowadays almost considered classical, such as affinity chromatography and ultrafiltration,...
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Full text (MCPHS users only) |
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| Other Authors: | , |
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Weinheim [Germany] :
Wiley-VCH,
2015
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| Subjects: | |
| Local Note: | ProQuest Ebook Central |
MARC
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| 245 | 0 | 0 | |a Analyzing biomolecular interactions by mass spectrometry / |c edited by Jeroen Kool, Wilfried M.A. Niessen. |
| 264 | 1 | |a Weinheim [Germany] : |b Wiley-VCH, |c [2015] | |
| 264 | 4 | |c ©2015 | |
| 300 | |a 1 online resource : |b illustrations (some color) | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |a Analyzing Biomolecular Interactions by Mass Spectrometry -- Contents -- List of Contributors -- Preface -- Abbreviations -- Chapter 1 Introduction to Mass Spectrometry, a Tutorial -- 1.1 Introduction -- 1.2 Figures of Merit -- 1.2.1 Introduction -- 1.2.2 Resolution -- 1.2.3 Mass Accuracy | |
| 505 | 8 | |a 1.2.4 General Data Acquisition in MS 1.3 Analyte Ionization -- 1.3.1 Introduction -- 1.3.2 Electrospray Ionization -- 1.3.3 Matrix-Assisted Laser Desorption Ionization -- 1.3.4 Other Ionization Methods -- 1.3.5 Solvent and Sample Compatibility Issues | |
| 505 | 8 | |a 1.4 Mass Analyzer Building Blocks 1.4.1 Introduction -- 1.4.2 Quadrupole Mass Analyzer -- 1.4.3 Ion-Trap Mass Analyzer -- 1.4.4 Time-of-Flight Mass Analyzer -- 1.4.5 Fourier Transform Ion Cyclotron Resonance Mass Spectrometer -- 1.4.6 Orbitrap Mass Analyzer | |
| 505 | 8 | |a 1.4.7 Ion Detection 1.5 Tandem Mass Spectrometry -- 1.5.1 Introduction: Tandem-in-Time and Tandem-in-Space -- 1.5.2 Ion Dissociation Techniques -- 1.5.3 Tandem Quadrupole MS-MS Instruments -- 1.5.4 Ion-Trap MS n Instruments -- 1.5.5 Tandem TOF (TOF-TOF) Instruments | |
| 505 | 8 | |a 1.5.6 Hybrid Instruments (Q-TOF, Q-LIT, IT-TOF) 1.5.7 MS-MS and MSn in FT-ICR-MS -- 1.5.8 Orbitrap-Based Hybrid Systems -- 1.5.9 Ion-Mobility Spectrometry-Mass Spectrometry -- 1.6 Data Interpretation and Analytical Strategies -- 1.6.1 Data Acquisition in MS Revisited | |
| 520 | |a This monograph reviews all relevant technologies based on mass spectrometry that are used to study or screen biological interactions in general. Arranged in three parts, the text begins by reviewing techniques nowadays almost considered classical, such as affinity chromatography and ultrafiltration, as well as the latest techniques. The second part focusses on all MS-based methods for the study of interactions of proteins with all classes of biomolecules. Besides pull down-based approaches, this section also emphasizes the use of ion mobility MS, capture-compound approaches, chemical proteomi. | ||
| 588 | 0 | |a Online resource; title from PDF title page (EBSCO, viewed February 18, 2015). | |
| 590 | |a ProQuest Ebook Central |b Ebook Central Academic Complete | ||
| 650 | 0 | |a Biomolecules |x Analysis. | |
| 650 | 0 | |a Mass spectrometry. | |
| 650 | 2 | |a Mass Spectrometry |x methods | |
| 650 | 2 | |a Mass Spectrometry | |
| 650 | 7 | |a mass spectrometry. |2 aat | |
| 700 | 1 | |a Kool, Jeroen, |e editer. | |
| 700 | 1 | |a Niessen, W. M. A. |q (Wilfried M. A.), |d 1956- |e editer. | |
| 758 | |i has work: |a Analyzing biomolecular interactions by mass spectrometry (Text) |1 https://id.oclc.org/worldcat/entity/E39PCFFtxqd3WFJ7DCpWyMRJwy |4 https://id.oclc.org/worldcat/ontology/hasWork | ||
| 776 | 0 | 8 | |i Print version: |t Analyzing biomolecular interactions by mass spectrometry. |d Weinheim, Germany : Wiley-VCH Verlag GmbH & Co., ©2015 |h xxii, 378 pages |z 9783527334643 |
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