Basic Immunology Functions and Disorders of the Immune System.
Understand all the essential concepts in immunology with Basic Immunology: Functions and Disorders of the Immune System! This concise, focused text provides you with an up-to-date, accessible introduction to the workings of the human immune system. Efficiently master the immunology information you n...
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Full text (MCPHS users only) |
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| Main Author: | |
| Other Authors: | , |
| Format: | Electronic eBook |
| Language: | English |
| Published: |
London :
Elsevier Health Sciences,
2012
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| Edition: | 4th ed. |
| Subjects: | |
| Local Note: | Ebook Library |
Table of Contents:
- Front cover; Student Consult page; Basic Immunology; Copyright page; Dedication; Preface; Table of Contents; 1 Introduction to the Immune System; Innate and Adaptive Immunity; Types of Adaptive Immunity; Properties of Adaptive Immune Responses; Specificity and Diversity; Memory; Other Features of Adaptive Immunity; Cells of the Immune System; Lymphocytes; Antigen-Presenting Cells; Effector Cells; Tissues of the Immune System; Peripheral Lymphoid Organs; Lymphocyte Recirculation and Migration into Tissues; Overview of Immune Responses to Microbes; Early Innate Immune Response to Microbes.
- Adaptive Immune ResponseCapture and Display of Microbial Antigens; Cell-Mediated Immunity: Activation of T Lymphocytes and Elimination of Cell-Associated Microbes; Humoral Immunity: Activation of B Lymphocytes and Elimination of Extracellular Microbes; Decline of Immune Responses and Immunologic Memory; Summary; Review Questions; 2 Innate Immunity; General Features and Specificity of Innate Immune Responses; Cellular Receptors for Microbes and Damaged Cells; Toll-Like Receptors; NOD-Like Receptors and the Inflammasome; Other Cellular Receptors of Innate Immunity.
- Components of Innate ImmunityEpithelial Barriers; Phagocytes: Neutrophils and Monocytes/Macrophages; Dendritic Cells; Mast Cells; Natural Killer Cells; Other Classes of Lymphocytes; Complement System; Other Plasma Proteins of Innate Immunity; Cytokines of Innate Immunity; Innate Immune Reactions; Inflammation; Recruitment of Phagocytes to Sites of Infection and Tissue Damage; Phagocytosis and Destruction of Microbes; Antiviral Defense; Regulation of Innate Immune Responses; MicrobIAL Evasion of Innate Immunity; Role of Innate Immunity in Stimulating Adaptive Immune Responses; Summary.
- Review Questions3 Antigen Capture and Presentation to Lymphocytes; Antigens Recognized by T Lymphocytes; Capture of Protein Antigens by Antigen-Presenting Cells; Structure and Function of Major Histocompatibility Complex Molecules; Structure of MHC Molecules; Properties of MHC Genes and Proteins; Peptide Binding to MHC Molecules; Processing and Presentation of Protein Antigens; Processing of Internalized Antigens for Display by Class II MHC Molecules; Processing of Cytosolic Antigens for Display by Class I MHC Molecules; Cross-Presentation of Internalized Antigens to CD8+ T Cells.
- Physiologic Significance of MHC-Associated Antigen PresentationFunctions of Antigen-Presenting Cells in Addition to Antigen Display; Antigens Recognized by B Cells and Other Lymphocytes; Summary; Review Questions; 4 Antigen Recognition in the Adaptive Immune System; Antigen Receptors of Lymphocytes; Antibodies; T Cell Receptors for Antigens; Development of Immune Repertoires; Early Lymphocyte Development; Production of Diverse Antigen Receptors; Maturation and Selection of B Lymphocytes; Maturation and Selection of T Lymphocytes; Summary; Review Questions; 5 T Cell-Mediated Immunity.
