Applied biopharmaceutics & pharmacokinetics
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| Online Access: |
Full text (MCPHS users only) |
|---|---|
| Main Authors: | , |
| Corporate Author: | |
| Format: | Electronic eBook |
| Language: | English |
| Published: |
New York :
McGraw-Hill Education,
2016
|
| Edition: | Seventh edition. |
| Subjects: |
Table of Contents:
- Introduction to biopharmaceutics and pharmacokinetics
- Mathematic fundamentals in pharmacokinetics
- Biostatistics
- One compartment open model : IV bolus injection
- Multicompartmental models : IV bolus injection
- Intravenous infusion
- Drug elimination and clearance
- Pharmacokinetics of oral absorption
- Multiple dosage regimens
- Nonlinear pharmacokinetics
- Physiologic drug distribution and protein binding
- Renal and hepatic elimination of drugs
- Pharmacogenetics and drug metabolism
- Physiologic factors related to drug absorption
- Biopharmaceutic considerations in drug product design
- Drug product performance, in vivo : bioavailability and bioequivalence
- Biopharmaceutic aspects of the active pharmaceutical ingredient and pharmaceutical equivalence
- Impact of biopharmaceutics on drug product quality and clinical efficacy
- Modified release drug products and drug devices
- Targeted drug delivery systems and biotechnology products
- Relationship between pharmacokinetic and pharmacodynamics
- Application of pharmacokinetics in clinical situations
- Application of pharmacokinetics in specific populations
- Dosage adjustment in renal and hepatic disease
- Empirical models, mechanistic models, statistical moment and noncompartmental analysis.
