Renewing the stuff of life : stem cells, ethics, and public policy by Cohen, Cynthia B.

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Regenerative medicine and cell therapy

Table of Contents: “…Stem Cells; Therapeutical Potential of Stem Cells; Embryonic Stem Cells, a Promise of Therapeutic Applications; Mesenchymal Stem Cell Characterization; Mesenchymal Stem Cells; Mesenchymal Stem Cells in Regenerative Medicine; Umbilical Cord Mesenchymal Stem Cells: Biology and Clinical Application; Umbilical Cord Blood: From Current Use to Future Applications; Adipose Stem Cells: Identification, Properties and Interest for Clinical Applications; Circulating Stem Cells Including Endothelial Progenitor Cells…”
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Bones and cartilage : developmental and evolutionary skeletal biology by Hall, Brian K. (Brian Keith), 1941-

Table of Contents: “…Types of skeletal tissues -- Bone -- Cartilage -- Invertebrate cartilages -- Intermediate tissues -- An evolutionary perspective -- Horns and ossicones -- Antlers -- Tendons and sesamoids -- Embryonic stem cells -- Stem cells in adults -- Osteo- and chondroprogenitor cells -- Dedifferentiation provides progenitor cells for jaws and long bones -- Dedifferentiation and urodele amphibian limb regeneration -- Cells to make and cells to break -- Skeletal origins : somitic mesoderm -- Skeletal origins : neural crest -- Epithelial-mesenchymal interactions -- The membranous skeleton : condensations -- From condensation to differentiation -- Skulls, eyes and ears : condensations and tissue interactions -- Chondrocyte diversity -- Cartilage diversity -- Osteoblast and osteocyte diversity -- Bone diversity -- Maintaining differentiated chondrocytes -- Maintenance awry : achondroplasia -- Restarting mammalian articular chondrocytes -- Repair of fractures and regeneration of growth plates -- Initiating skeletal growth -- Form, polarity and long-bone growth -- Long bone growth : a case of crying Wolff? …”
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Cancer stem cells

Table of Contents: “…Oxytocin and vasopressin systems: oxytocin, vasopressin, and their interplay with gonadal steroids: essentials of cancer stem cells and conceptual modeling -- Theoretical and experimental foundations of the "cancer stem cell" model -- The hallmarks of prostate cancer stem cells -- Self-renewal, induced proliferation, and autonomous cell growth represent distinct modes of cell multiplication: relevance to the cancer stem cell theory -- Human embryonic stem cells and cancer: modeling disease in a dish -- Cancer stem cell as a result of a reprogramming-like mechanism: implications in tumor development and treatment -- A cancer stem cell model: an insight into the conversion of induced pluripotent stem cells to cancer stem-like cells -- Altruistic stem cells and cancer stem cells -- The emerging concept of EMT-induced cancer stem cells -- Models to study chronic myeloid leukemia cancer stem cells -- Cancer stem cells in melanoma: biomarkers and mathematical models -- Stem cells in liquid tumors -- Acute myeloid leukemia stem cells: updates and controversies -- Leukemia-initiating cells in acute lymphoblastic leukemia -- Stem cells in solid tumors -- Lung cancer stem cells and resistance to radiotherapy -- Prostate cancer cell heterogeneity and prostate cancer stem cells -- Glioblastoma stem cells drive tumor recurrence and patient relapse: what's the evidence? …”
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Cancer metastasis and cancer stem cell/niche

Table of Contents: “…ENHANCED STEMNESS AND ALTERED GLYCAN EXPRESSION BY TUMOR HYPOXIAAcquisition of Resistance to Hypoxia by Cancer Cells in Advanced Stage of Cancers; Normal Stem Cells and Their Hypoxic Niches; STEM CELLS AND GLYCAN ALTERATION IN EPITHELIO-MESENCHYMAL TRANSITION; Glycan Alteration in Epithelio-mesenchymal Transition of Cancer Cells; Normal Stem Cells and Plasticity to Undergo EMT/MET; GLYCANS ASSOCIATED WITH HUMAN EMBRYONIC STEM CELLS AND CANCER STEM CELLS; Appearance of Classical Human Embryonic Stem Cell Marker Glycans, SSEA-3/-4, in Cancer Stem Cells.…”
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Perspectives in stem cell research

Table of Contents: “…PERSPECTIVES IN STEM CELL RESEARCH; PERSPECTIVES IN STEM CELL RESEARCH ; CONTENTS ; PREFACE ; STEM CELL RESEARCH* ; SUMMARY ; OVERVIEW OF BASIC RESEARCH AND POTENTIAL APPLICATIONS ; Stem Cells from Embryos or Fetal Tissue ; Stem Cells from Adult Tissue or Umbilical Cord Blood ; Potential Applications of Stem Cell Research ; Current Federal Regulatory Landscape ; State Legislation on Embryonic Stem Cell Research ; Congressional Actions ; International Actions on Embryonic Stem Cell Research ; Ethical Issues ; REFERENCES ; CANCER STEM CELLS ; ABSTRACT ; INTRODUCTION ; STEM CELLS.…”
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Stem cell research.

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The shattered self : the end of natural evolution by Baldi, Pierre

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Biomaterials and stem cells in regenerative medicine

Table of Contents: “…Umbilical Cord Matrix Mesenchymal Stem Cells: A Potential Allogenic Cell Source for Tissue Engineering and Regenerative Medicine; Chapter 22. Human Embryonic Stem Cells and Tissue Regeneration; Chapter 24. …”
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Biomechatronic design in biotechnology : a methodology for development of biotechnological products by Mandenius, Carl-Fredrik, 1954-

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Handbook of cardiac stem cell therapy

Table of Contents: “…Overview of adult stem cell therapy in cardiac disease / Georgios Nteliopoulos, Natas̮a Levic̮ar and Ioannis Dimarakis -- 3. Embryonic stem cells and their therapeutic potential / Tomo S̮arić [and others] -- 4. …”
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Paranoid science : the Christian Right's war on reality by Alumkal, Antony William, 1969-

Table of Contents: “…Stem cell research : Basic issues -- From abortion to embryonic stem cells -- Arguments against embryonic stem cell research and cloning -- The dangers of eugenics and transhumanism -- Euthanasia's slippery slope -- Why the slippery slope is slippery logic -- Is Oregon the new Netherlands? …”
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Science and Political Controversy. by Newton, David

Table of Contents: “…Oppenheimer, the Manhattan Project, and ReactionThe Space Race and the Apollo Program; Big Science, Little Science; The Superconducting Super Collider; The Strategic Defense Initiative; Science Interruptus; The Evils of Marijuana, ; Issues of Human Sexuality; Abstinence-Only Education; Plan B; Global Climate Change; Conclusion; 3 PERSPECTIVES; Introduction; The Politics of Human Embryonic Stem Cells, Sandy Becker; Kitzmiller v. Dover in Focus, Glenn Branch; Science Is Not a Liberal Conspiracy, Allan B. …”
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Stem Cells and Regenerative Medicine : Volume II: Embryonic and Adult Stem Cells. by Taupin, Phillippe

Table of Contents: “…STEM CELLS AND REGENERATIVE MEDICINE, VOLUME II: EMBRYONIC AND ADULT STEM CELLS; STEM CELLS AND REGENERATIVE MEDICINE, VOLUME II: EMBRYONIC AND ADULT STEM CELLS; Contents ; Introduction ; References ; Derivation of Embryonic Stem Cells for Cellular Therapy: Challenges and New Strategies ; Abstract; 1. …”
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Principles of stem cell biology and cancer : future applications and therapeutics

Table of Contents: “…Isolation and characterisation of human embryonic stem cells and future applications in tissue engineering therapies / Christian Unger, James Hackland, David Preskey, Harry Moore -- Epigenetics, stem cell pluripotency and differentiation / Maria J. …”
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Emerging technologies : from hindsight to foresight

Table of Contents: “…Stakeholder Participation and Regulatory Development / Stuart Smyth -- In the Stem Cell Fields When Human Dignity Is Not Enough : Embryonic Stem Cell Research and Human Cloning in Canada / Tania Bubela and Timothy Caulfield -- Banking on trust : Issues of Informed Consent in Pharmacogenetic Research / Rose Geransar -- Pharmacogenomic Promises : Reflections on Semantics, Genohype, and Global Justice / Bryn Williams-Jones and Vural Ozdemir -- Envisioning Race and Medicine : BiDil and the Insufficient Match between Social Groups and Genotypes / Benjamin R. …”
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Epigenetics : current research and emerging trends

Table of Contents: “…3: Sirtuin Deacetylases in Fungi: Connecting Metabolism to Lifecycle Progression, Stress Response and Genome StabilityProperties of sirtuins; Subfamilies of sirtuins; Contributions of sirtuins to fungal biology; 4: Development-linked Differences in Cytosine 5-Hydroxymethylation in Mammalian DNA: Relationship to 5-Methylcytosine and Function; Introduction; Analytic methods used to study 5hmC in vertebrate DNA; DNA hydroxymethylation in very early mammalian development: embryonic stem cells (ESC); DNA hydroxymethylation changes during development: neurogenic, germline and adipogenic lineages.…”
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Modern Biopharmaceuticals : Recent Success Stories. by Kn?blein, J?rg

Table of Contents: “…2.1 Introduction2.2 Derivation and Growth of hESC; 2.3 Signaling Pathways and Transcription Factors; 2.4 Differentiation and Applications of hESC; 2.5 Patient-Specific Nuclear Transfer Stem Cells; 2.6 Patient-Specific Pluripotent Cells Through Direct Reprogramming of Adult Somatic Cells; 2.7 Concluding Remarks and Outlook; References; 3 Pluripotent Stem Cell-Derived Cardiomyocytes for Industrial and Clinical Applications; 3.1 Introduction; 3.2 Pluripotent Stem Cells; 3.2.1 Embryonic Stem Cells; 3.2.2 Parthenogenetic Stem Cells; 3.2.3 Germline Pluripotent Stem Cells…”
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Stem Cells : From Mechanisms to Technologies

Table of Contents: “…Comparative transcriptomics for global functional profiling of embryonic stem cells / Yu Sun and Ming Zhan. ch. 4. A common integrative nuclear signaling module for stem cell development / Michal K. …”
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Advances in medicine and biology. Volume 7

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Molecular Medicine An Introduction. by Kurreck, Jens

Table of Contents: “…Chapter 10: Recombinant Protein Drugs -- 10.1 Production of Recombinant Proteins -- 10.2 Classes of Recombinant Drugs -- References -- Chapter 11: Gene Therapy -- 11.1 Types of Gene Therapy -- 11.2 Methods of Gene Transfer -- 11.3 Tissue Specificity of Gene Transfer and Gene Expression -- 11.4 Applications of Gene Therapy -- 11.5 Future Prospects -- References -- Chapter 12: Stem Cells -- 12.1 Embryonic Stem Cells -- 12.2 Adult Stem Cells -- 12.3 Induced Pluripotent Stem Cells -- 12.4 Transdifferentiation and Direct Reprogramming -- 12.5 Differentiation of Stem Cells…”
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A laboratory guide to the mammalian embryo

Table of Contents: “…Capco -- Human embryonic stem cells / Susan E. Lazendorf, Catherine A. Boyd, and Diane L. …”
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Biomaterials from Nature for Advanced Devices and Therapies. by Neves, Nuno M.

Table of Contents: “…3 Gelatin-Based Biomaterials For Tissue Engineering And Stem Cell Bioengineering3.1 Introduction; 3.2 Crosslinking of Gelatin; 3.3 Physical Properties of Gelatin; 3.4 Application of Gelatin-Based Biomaterials In Tissue Engineering; 3.4.1 Cardiovascular Tissue Engineering; 3.4.2 Bone Tissue Engineering; 3.4.3 Hepatic Tissue Engineering; 3.4.4 Ophthalmology; 3.4.5 Dermatology ; 3.4.6 Miscellaneous Applications ; 3.5 Gelatin for Stem Cell Therapy; 3.5.1 Embryonic Stem Cells; 3.5.2 Adult Stem Cells; 3.5.3 Induced Pluripotent Stem Cells; 3.6 Application of Gelatin In Delivery Systems.…”
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Stem cells in regenerative medicine : science, regulation and business strategies

Table of Contents: “…Caplan and Erkki Ruoshlati -- Hematopoietic stem cells / Steve Wolpe and Lynnet Koh -- MSCs: the new medicince / Arnold Caplan -- Innovation and commercialization of induced pluripotent stem cells / Shintaro Sengoku -- Embryonic stem cells / Rachel Eiges, Benjamin E. Reubinoff and Charles Irving -- Allogeneic versus autologous stem cell transplantation in regenerative medicine / Kathy Trzaska-Accurso and Pranela Rameshwar -- Clinical immunological barriers to regenerative medicine: do they matter? …”
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The eureka! moment : 100 key scientific discoveries of the 20th century by Lee, Rupert

Table of Contents: “…Interferons (Isaacs and Lindemann, 1957 Isaacs et al, 1957); Prions (Prusiner et al, 1983); HIV (Barre-Sinoussi et al, 1983); Helicobacter pylori (Marshall et al, 1985); Embryonic Stem Cells Grown Artificially (Gearhart, 1997); HISTORY OF LIFE; First Clues About How Life Began (Miller, 1953); The Early Presence of Life on Earth (Mojzsis et al, 1996); The Origin of Higher Organisms (Sagan, 1967); Nemesis of the Dinosaurs (Alvarez et al, 1980); 'Lucy' (Johanson and Taieb, 1976); The 'Taung Child' (Dart, 1925); BIOLOGY; Conditioned Reflexes (Pavlov, 1906); Bacteriophages (d'Herelle, 1917).…”
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Regenerative medicine

Table of Contents: “…Colloquium Neuroectodermal differentiation from mouse multipotent adult progenitor cells METHODS -- RESULTS -- DISCUSSION -- Colloquium Ingestion of bacterially expressed double-stranded RNA inhibits gene expression in planarians -- MATERIALS AND METHODS -- RESULTS -- DISCUSSION -- Colloquium Genetic and functional differences between multipotent neural and pluripotent embryonic stem cells -- MATERIALS AND METHODS -- RESULTS -- DISCUSSION -- Colloquium Indian hedgehog and ß-catenin signaling: Role in the sebaceous lineage of normal and neoplastic mammalianâ€?…”
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Telomeres : function, shortening and lengthening

Table of Contents: “…Eller -- Telomere lengthening from oocyte to embryonic stem cell / Eva Pericuesta [and others] -- Transcriptional activity at the telomeres of chironomus (diptera) : its possible role in the lengthening of the telomeres / J.L. …”
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Ethical and legal debates in Irish healthcare : confronting complexities

Table of Contents: “…Examining Ireland's failure to regulate embryonic stem cell research: Ciara Staunton.…”
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Stem cell labeling for delivery and tracking using noninvasive imaging

Table of Contents: “…Human embryonic stem cells / Richard P. Davis, Edouard G. Stanley, and Christine L. …”
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Stems cells in toxicology and medicine

Table of Contents: “…Intro -- Title Page -- Copyright Page -- Contents -- List of Contributors -- Preface -- Acknowledgements -- Part I -- Chapter 1 Introduction -- References -- Chapter 2 Application of Stem Cells and iPS Cells in Toxicology -- 2.1 Introduction -- 2.2 Significance -- 2.3 Stem Cell (SC) Classification -- 2.4 Stem Cells and Pharmacotoxicological Screenings -- 2.5 Industrial Utilization Showcases Stem Cell Technology as a Research Tool -- 2.6 Multipotent Stem Cells (Adult Stem Cells) Characteristics and Current Uses -- 2.7 Mesenchymal Stem Cells (Adult Stem Cells) -- 2.8 Hematopoietic Stem Cells (Adult Stem Cells) -- 2.9 Cardiotoxicity -- 2.10 Hepatotoxicity -- 2.11 Epigenetic Profile -- 2.12 Use of SC and iPSC in Drug Safety -- 2.12.1 Potential Benefits of Stem Cell Use in Other Areas -- 2.12.2 Methodologies -- 2.12.3 Economic Benefits of Stem Cell Use -- 2.13 Conclusions and Future Applications -- Acknowledgments -- References -- Chapter 3 Stem Cells: A Potential Source for High Throughput Screening in Toxicology -- 3.1 Introduction -- 3.2 Stem Cells -- 3.2.1 Embryonic Stem Cells (ESCs) -- 3.2.2 Foetal Stem Cells -- 3.2.3 Adult Stem Cells -- 3.2.4 Adult Stem Cells in Other Tissues -- 3.3 High Throughput Screening (HTS) -- 3.3.1 Current Strategies and Types of High Throughput Screening -- 3.3.2 In Vitro Biochemical Assays -- 3.3.2.1 Fluorescent Based Assays -- 3.3.2.2 Luminescence-Based Assays -- 3.3.2.3 Colorimetric and Chromogenic Assays -- 3.3.2.4 Mass Spectroscopy (MS) Based Detection Assays -- 3.3.2.5 Chromatography-Based Assays -- 3.3.2.6 Immobilization and Label-Free Detection Assays -- 3.3.3 Cell-Based Assays -- 3.3.3.1 Reporter Gene Assays -- 3.3.3.2 Cell-Based Label Free Readouts -- 3.4 Need for a Stem Cell Approach in High Throughput Toxicity Studies -- 3.5 Role of Stem Cells in High Throughput Screening for Toxicity Prediction.…”
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Females are mosaics : X inactivation and sex differences in disease by Migeon, Barbara R.

Table of Contents: “…Mouse-Human Hybrids Separate Inactive from Active X; 5.5. Mouse Embryonic Stem Cells for Manipulating the Early Steps in X Inactivation; 5.6. …”
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The Fertility Promise Medicine Demystified. by Hollands, Peter

Table of Contents: “…-- Laboratory Automation -- Artificial Intelligence -- Quantum Biology and Quantum Physics -- PRP and Stem Cells -- Embryonic Stem Cells and Hybrids -- KEY POINTS OF CHAPTER 11 -- A Final Thought -- Peter Hollands -- INTRODUCTION -- FERTILITY PATIENTS.…”
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Newshour medical ethics and issues anthology

Table of Contents: “…Constitution and Assisted Suicide (6:05) -- Embryonic Stem Cell Debate (3:26) -- Ethical Issues of Stem Cell Production (4:18)…”
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Engineering Neural Tissue from Stem Cells by Willerth, Stephanie

Table of Contents: “…3 Discovery of Neural Stem Cells and Their Applications for Nervous System Repair -- 4 Derivation of Human Embryonic Stem Cells and Their Applications for Nervous System Repair -- 5 Derivation of Induced Pluripotent Stem Cells and Their Applications for Nervous System Repair -- 6 Direct Reprogramming of Mature Cells Into Functional Neural Cells -- 7 Concluding Remarks on Stem Cells and Their Potential as Cell Therapies -- Relevant Resources -- References -- Chapter 4 Design considerations when engineering neural tissue from stem cells -- 1 Introduction -- 2 Chemical Properties of Neural Tissue -- 2.1 Proteins of the Extracellular Matrix and Their Function -- 2.1.1 Collagen -- 2.1.2 Fibronectin -- 2.1.3 Laminin -- 2.1.4 Elastin -- 2.1.5 Glycoproteins found in the extracellular matrix of the nervous system -- 2.2 Polysaccharides Found in the Extracellular Matrix and Their Function -- 2.2.1 Hyaluronan/hyaluronic acid -- 2.2.2 Chondroitin sulfate -- 2.2.3 Heparin and heparan sulfate -- 2.2.4 Keratan sulfate/keratosulfate -- 2.3 Composition of the Extracellular Matrix of the Brain and the Spinal Cord -- 2.4 Composition of the Extracellular Matrix in the Peripheral Nervous System -- 2.5 Role of Growth Factors in the Extracellular Matrix -- 2.6 The Role of Small Molecules in Neuronal Development -- 3 Mechanical Properties of Neural Tissue -- 3.1 The Physical Topography of the Extracellular Matrix and Its Effect on Cellular Behavior -- 3.2 The Mechanical Properties of Neural Tissue and How They Relate to Stem Cell Behavior -- 4 Implications for Design of Biomaterial Scaffolds -- Additional Resources -- Cell Biology Textbooks for Further Reading About the Extracellular Matrix -- Textbooks About Biomaterials for Further Reading -- Textbooks About Tissue Engineering for Further Reading -- Companies That 3D Print Tissues -- References.…”
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Etiology and morphogenesis of congenital heart disease : from gene function and cellular interaction to morphology

Table of Contents: “…Conduction system and arrhythmia -- Regulation of vertebrate conduction system development -- Cardiac Pacemaker Development from a Tertiary Heart Field -- Endothelin receptor type A expressing cell population in the inflow tract contributes to chamber formation -- Specific isolation of HCN4 positive cardiac pace-making cells derived from embryonic stem cell -- Part IX. Current molecular mechanism in cardiovascular development -- Combinatorial functions of transcription factors and epigenetic factors in heart development and disease -- Pcgf5 contributes to PRC1 (Polycomb repressive complex 1) in developing cardiac cells -- Non-coding RNAs in cardiovascular disease -- Part X. iPS cells and regeneration in congenital heart diseases -- Human pluripotent stem cells to model congenital heart disease -- Engineered cardiac tissues generated from immature cardiac and stem-cell derived cells: Multiple approaches and outcomes -- Dissecting the left heart hypoplasia by pluripotent stem cells -- Lentiviral gene transfer to iPS cells; toward the cardiomyocyte differentiation of Pompe disease-specific iPS cells -- Molecular analysis of long-term cultured cardiac stem cells for cardiac regeneration -- Epicardial contribution in neonatal heart regeneration -- Part XI. …”
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Introduction to biotechnology by Thieman, William J., Palladino, Michael Angelo

Table of Contents: “…Note continued: Regulations Governing Embryonic Stem Cell and Therapeutic Cloning in the United States -- Questions & Activities -- Case Study: Personal Genomics Helps Elizabeth Davis Walk Again -- 12.1. …”

The human trial

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Bioethics and the future of stem cell research by Hyun, Insoo, 1970-

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Frontline. My father, my brother, and me

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Experiments in democracy : human embryo research and the politics of bioethics by Hurlbut, J. Benjamin

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