NTP research report on absence of formaldehyde-induced neoplasia in Trp53 haploinsufficient mice exposed by inhalation /

Formaldehyde inhalation is linked to nasal cancer and leukemia in humans. Formaldehyde-induced DNA-protein crosslinks and enhanced cell proliferation are important in the pathogenesis of nasal cancer and, potentially, leukemia. Mutations in the tumor suppressor gene Trp53 have been associated with f...

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Bibliographic Details
Online Access: http://www.ncbi.nlm.nih.gov/books/NBK513193/
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Main Author: Morgan, D. (Daniel L.) (Author)
Format: Electronic eBook
Language:English
Published: Research Triangle Park, North Carolina : National Toxicology Program, 2017
Series:Research report (National Toxicology Program (U.S.)) ; 3.
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